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Carnitine deficiencies also are found in patients undergoing hemodialysis or those affected by any one of various organic acidemias/acidurias (e.g
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It is still not clear how possession of the APOE ε4 allele increases AD risk, but ApoE appears to be required for Aβ aggregation and ApoE ε4 has been shown to be the most efficient at promoting such oligomerization (284)
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