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BACH1 is increased in cystic fibrosis and chronic obstructive pulmonary disease (COPD) patients and is linked to respiratory impairment
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MLL-AF4 B-ALL is highly aggressive and has a very poor overall prognosis which tends to be refractory to conventional anti-leukemia therapies due to the development of resistance and relapse ( MLL-AF4 B-ALL cells by preventing the degradation of MLL-AF4 protein (Liu et al., 2014)
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