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Mitochondrial Medicine for Aging and Neurodegenerative Diseases | NeuroMolecular Medicine | Springer Nature Link
The same purification protocol as described above was also used for the Strep–ZAK(T161A/165A) and FLAG–ZAK(K45M/K394D) pull-downs as well as for the FLAG–ZAK(K45M) pull-down performed without previous challenging cells with ANS (see also Extended Data Fig
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Thus, VEGF-stimulated TK activation via ligand binding to the VEGFR extracellular domain is part of a widely conserved mechanism across the RTK family
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