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The study reveals that the mechanism of NAD(P)H in ferroptosis involves the membrane-associated RING-CH-type finger 6 (MARCHF6) E3 ubiquitin ligase in the transmembrane endoplasmic reticulum interacts with NAD(P)H through its C-terminal region, enhancing its activity and reducing ferroptosis (109)
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The most common side effects are mild: slight water retention, flushing, or injection site reactions
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