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In dermatology practice, it is mainly used in the treatment of dermatocompulsions and pseudoporphyria.8,9 In a non-randomized trial with 30 Egyptian women, one group (n = 10) received oral glutathione 500 mg/day, while another used topical glutathione 2%, and a third used placebo for four weeks, always associated with SPF 30 sunscreen
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Pathologically, ALS is characterized by motor neuron degeneration and a constellation of co-occurring molecular abnormalities, including excitotoxicity, mitochondrial dysfunction, oxidative stress, necrosis, altered proteostasis, impaired cytoskeletal trafficking, DNA damage, and dysfunctional RNA metabolism
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