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When the homeostasis of copper ion is disrupted, this imbalance can trigger cytotoxicity and induce cell death through various pathways, including reactive oxygen species (ROS) accumulation, proteasome inhibition, and mitochondrial dysfunction
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Even setting aside the substantial fraction of the world’s population that lives in chronic food shortage, the human equivalent of a mouse’s ad lib feeding would seem to be more like prisoners in a cell with little to do, minimal opportunity for physical activity, and an infinite supply of food within easy arm’s reach
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