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Studies from human stem-cell-derived dopaminergic neurons have shown that neurons harboring the endogenous aSyn-A53T mutation have increased kinetics of NO synthesis and are more susceptible to RNS-toxins 59,61

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For example, for claims with dates of service between October 1, 2026, through December 31, 2026, covered entities that choose to submit data elements from Part D 340B claims would submit the data to the 340B repository no later than March 31, 2027