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Both schizophrenia and vascular dementia involve cholinergic dysfunction contributing to cognitive impairment, but schizophrenia is mainly associated with ฮฑ7 nicotinic acetylcholine receptor (nAChR) abnormalities in frontalโcingulate regions, whereas VaD predominantly affects ฮฑ4ฮฒ2 nAChRs in hippocampal and subcortical structures (179)
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[DOI] [PMC free article] [PubMed] [Google Scholar] 180.Liu T., Kong X., Qiao J., Wei J
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