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Tear fluid shows promise as a non-invasive source for AD biomarkers, offering novel disease insights, and potential utility for pre-screening prior to PET imaging
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Under the induction of oxidative stress, a part of HIF-1α is translocated to mitochondria, where it inhibits the respiratory chain by lowering the expression of mtDNA-encoded mRNA that responses to hypoxia, thus preventing the over-production of ROS and resisting oxidative stress
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