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Thus, as demonstrated here, the action of Semax on the expression of genes that ensure the formation and functioning of the vascular system in ischemic conditions also uncovered its possible vascular and regenerative properties, in addition to its neuroprotective and vasoactive effects

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Elevated levels of beta amyloid (Aβ) have been correlated with reduced spine density in vivo, as observed for AD as well as model systems for AD pathology (Davies et al., 1987