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While earlier studies suggested that nNOS is unlikely to be the mitochondrial NOS (mtNOS)46, subsequent studies suggest that mtNOS is nNOS or a spliced variant of it (likely nNOSα or nNOSμ), at least in the heart47
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Emerging research on the lactylation of astrocytes suggests that this novel PTM is more inclined to direct cellular processes towards beneficial outcomes, rather than being a driver of inflammation
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