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These investigations revealed that microglia can promote Aβ clearance through pathways such as LC3-associated endocytosis (LANDO), regulation of phagocytic receptors, and TREM2-dependent conversion to DAM, while cooperating with astrocytes and being influenced by APOE isoforms (266–270)
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This release of proinflammatory cytokines is directly proportional to exercise intensity and duration [257]
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