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Implementation: a biomarker-guided, compartment-aware algorithm Implement a biomarker-guided, compartment-aware algorithm: first, phenotype the redox problem with a multi-parameter panel that combines species reporters (DHE-HPLC to quantify O 2 ·− via 2-OH-E⁺, compartment-targeted HyPer to track H 2 O 2 ) (Meier et al
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The loading dose may be chosen to produce the amount of drug in the body that would eventually be reached by the infusion alone
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