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This understanding enabled the development of ruxolitinib (Opzelura®) , the first specific treatment for vitiligo approved by the FDA in 2022 and the EMA in 2023
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For instance, investigations analyzing the methylation patterns of genes such as DKK1, ERAP1, PDCD1, FOXO1, FOXO3a, LGR6, and IRF5 frequently involve sample sizes under 100 per group
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