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Frank Shallenberger, MD, HMD Archives - Townsend Letter

Evidence from clinical trials has validated riluzole’s effectiveness in extending median survival of ALS patients by two to three months and slowing the decline in respiratory capabilities, a significant marker of ALS progression (25)

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On the other hand, studies defining the decision-making process in appendicitis using artificial neural networks (ANNs) yielded impressive results (91% sensitivity with 85% specificity, and 100% sensitivity with 97% specificity) but ANNs are burdened with significant data overfitting, and hence, without proper validation can lead to overly optimistic results 33,34,35

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