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Epithalon (also spelled Epitalon or Epithalone) is a synthetic tetrapeptide developed from research into pineal gland extracts, particularly a bovine pineal extract called epithalamin. It was largely pioneered by Russian gerontologist Vladimir

In vitro studies demonstrated that it scavenged H 2 O 2 and increased glutathione synthesis twice as effectively as NAC, and reduced H 2 O 2 release by polymorphonuclear leukocytes isolated from the blood of smokers with COPD

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(1997).Increased nuclear ploidy, not cell proliferation, is sustained in the peroxisome proliferator-treated rat liver