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Bifidobacterium longum and prebiotic interventions restore early-life high-fat/high-sugar diet-induced alterations in feeding behavior in adult mice | Nature Communications

[0265] Additional eukaryotic expression systems that introduce N-linked glycosylation to generate a functional sHASEGP product can be tested by introducing a human sHASEGP expression plasmid into said cells and testing for neutral activity

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However, since then, the field has continued to progress rapidly, with recent animal studies and early-phase clinical trials that highlight the efficacy and feasibility of IN delivery for iron chelators (Boyuklieva et al., 2024