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Key Points CSA-AKI is the second most common cause of AKI in the intensive care setting and is associated with increased mortality The pathophysiology of CSA-AKI is very complex and probably includes renal ischaemia–reperfusion injury, inflammation, oxidative stress, haemolysis and nephrotoxins To date, no consensus definition for CSA-AKI exists, but the KDIGO criteria for AKI are commonly used in clinical practice To date, no pharmacological or non-pharmacological preventive strategies have been shown to reduce the occurrence of CSA-AKI in clinical trials The management of CSA-AKI requires a multifaceted approach Renal replacement therapy is necessary in 1–5% of patients with CSA-AKI and is associated with poor patient and renal prognosis, both in the short and long-term Abstract Cardiac surgery-associated acute kidney injury (CSA-AKI) is the most common clinically important complication in adult patients undergoing open heart surgery, and is associated with increased mortality and morbidity

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Size:1000 mcg/ml - 10 ml (Pack of 4)

Under 503B the test is different again, running through the 503B Bulks List or a drug-shortage connection