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In the late 1950s, a drug called thalidomide was widely prescribed in Europe and Australia as a highly effective treatment for morning sickness in pregnant women. The manufacturer assured doctors that the
Hcy-thiolactone/creatinine ratio was indicated as a novel acute myocardial infarction risk predictor in patients with suspected coronary artery disease, independent of traditional risk factors and Hcy, but modified by vitamin B6 catabolism 9
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