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4.3.1 Inhibition of USP25 to ameliorate Aβ pathology and neuroinflammation USP25 exacerbates AD through dual pathways, making it a high-value target
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Notably, CD44 + CD69 + T RM cells within hepatic CD8 + T cells, when activated by IL-15/IL-15Rα from hepatic CD103 + cDC1s of APAP mice, played a crucial role in inducing apoptosis of liver-infiltrating monocytes through direct cell-to-cell interactions and granzyme B secretion
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