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Oxidative Stress and Neurological Disorders Oxidative stress, an imbalance between the production of free radicals and the body's ability to counteract their harmful effects, has been implicated in the pathogenesis of numerous neurological disorders
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Besides Gpx1, Gpx4 displays preference for lipid hydroperoxides ( Figure 3 ), and hence plays a key role in protecting phospholipids, cholesteryl esters and cardiolipin and defense against apoptosis and maintenance of ETC and OXPHOS (Cole-Ezea et al., 2012)
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