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Although it is well-accepted that tight junctions are crucial for the maintenance of barrier integrity, the exact function of the individual tight junction proteins remain elusive

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Therefore, we reviewed several natural products with significant neuroprotective effects against hypoxia-induced neurological injury, including EGCG, ginkgolides, CA, Que, BBR, and curcumin, with common features including anti-inflammatory, anti-oxidative stress, and anti-apoptosis, as well as exerting neuroprotective effects through multiple pathways and targets