glutathione polyol pathway Aldose Reductase and the in Schwann Cells: Old and New Problems Diabetic neuropathy

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In a 2015 meta-analysis by Li et al[16], it was acknowledged that numerous randomised controlled trials have investigated the efficacy of lowering homocysteine with folic acid supplementation for CVD risk, but conflicting results have been reported

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Studies have confirmed that thyroid function will affect HPA axis activity, insulin sensitivity of glucose, lipid metabolism, and ovarian secretion function, resulting in hypercortisolism, insulin resistance, and sexual dysfunction (98–102)