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Intermittent fasting: a comprehensive review of cellular mechanisms, metabolic processes, and organ health | Journal of Umm Al-Qura University for Medical Science | Springer Nature Link
The ability to purify protein complexes enables detailed analysis of their functional roles and interactions within the cell
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Furthermore, the homozygous ApoE4-R136S mutation (ApoE4-Ch) was shown to rescue ApoE4-driven tau pathology, neurodegeneration, and neuroinflammation in tauopathy mouse models and human iPSC-derived neurons carrying human ApoE4 with either homozygous or heterozygous R136S mutations in late-onset AD
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