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In addition, in vivo studies in animal models of PD elevation of brain GSH by icv infusion of GEE have been reported to provide neuroprotection against oxidative stress caused by chronic mitochondrial impairment due to central delivery of MPP+ [116]

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TMPRSS6, also known as matriptase-2, negatively regulates the production of hepcidin and is a membrane-bound serine protease expressed in hepatocytes

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