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Evaluated with a hold-out test set containing 168 benzoylated molecules, Bz-MS achieved a median WCS value of 0.74 ± 0.03 (95% CI, n = 168) in predicting spectra for benzoylated molecules, which was significantly improved from the pre-trained model, ESI-MLP (median WCS = 0.53 ± 0.02, 95% CI, n = 168) (Fig