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Moreover, quercetin 3-O-β-D-glucuronide has been found to enhance skin hydration by upregulating the expression of genes related to moisturization in keratinocytes, such as transglutaminase-1 (TGM-1) and hyaluronan synthase (HAS)-1 ( 4.6 Anti-melanin and scarring effects of quercetin The inflammatory process in acne often triggers excessive melanin production, leading to abnormal melanin deposition and resulting in post-inflammatory hyperpigmentation (PIH) in affected individuals (Xue et al., 2011)
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