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More studies, possibly involving thromboelastography, are needed to investigate the exact cause of coagulation problems in these cases to inform treatment decision-making
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In vivo, however, due to its different quaternary structure, the ubiquitously expressed [77] mitochondrial Fe 2 S 2 -Grx2a cannot compensate for the iron deficiency phenotype caused by Fe 2 S 2 -Grx5 depletion or loss, in neither zebrafish [82] nor in humans [82,109]
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