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For instance, nanotherapeutics engineered to inhibit ACSL4 (a key mediator of ferroptosis) while activating regulatory T cells (Treg)—which modulate excessive immune responses—could synergistically address both oxidative stress and immune dysregulation, two core drivers of asthma progression
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(VII) miRNAs directly degrade messenger RNA or repress translation to regulate gene expression (Friedman et al., 2009)
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