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In ovarian stromal cells of PCOS patients, LH enhances CYP17A1 phosphorylation via the cAMP/PKA pathway, upregulating 17α-hydroxylase and 17,20-lyase activities and leading to excessive production of androstenedione and testosterone (58)
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These lines of evidence suggest that the role of CXCL12 and CXCR4 in atherosclerosis is still under debate
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