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Perhaps a fundamental rethinking of the mode of action for ADCs in autoimmune diseases is needed - for instance, developing ADCs based on entirely new concepts such as reversible modulation, spatiotemporally specific release, or cell reprogramming, thereby unleashing the novel potential of the ADC platform in the field of immunomodulation

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328 The researchers conducted the first experimental validation of the broad utility and readiness of the CogMol deep generation framework by synthesizing and testing a series of compounds designed to inhibit the SARS-CoV-2 S protein and M pro