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Biological potential and therapeutic effectiveness of hinokiflavone in medicine: the effective components of herbal medicines for treatment of cancers and associated complications

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Intriguingly, a Western diet high in PUFAs can induce intestinal inflammation in mice lacking one allele of GPX4 in IECs, which implies that dietary PUFAs may be a trigger of GPX4-restricted mucosal inflammation phenocopying aspects of human CD (143)