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For acute injuries with significant pain and swelling, some practitioners and experienced users suggest a higher loading approach during the first 3-5 days: 0.5 mg twice daily (1 mg total) before reducing to maintenance dosing
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doi: 10.1038/s41586-024-07396-y, PMID: [DOI] [PubMed] [Google Scholar] 27.Lawrence RA, Lawrence RM
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