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metabolite s-gamma-glu-cys glutathione Glutamyl cycle, 1 Glutamate cysteine ligase (GCL), 2 GM-Skincare
AKT activation because of PTEN loss upregulates xCT via GSK3β/NRF2, leading to inhibition of ferroptosis in PTEN-mutant tumor cells: Cell Reports
183 Notably, stimulation of the PI3K/AKT pathway was found to antagonize PTEN function to ameliorate LPS-mediated intestinal epithelial barrier disruption
GM-Skincare
Injection(s):Eight
doi: 10.1016/0003-9861(91)90160-K
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