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The benzoquinone ring in CoQ10 is derived from tyrosine, whereas the side chain originates from acetyl-CoA through the mevalonate pathway, a process also involved in cholesterol and lipid synthesis [20]
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In cancer research, pair GCL activity with GSH levels: elevated GCL but stagnant GSH suggests downstream bottleneck (e.g., glutathione synthetase deficiency)
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