glutathione redox cycle liver Metabolism - an overview تونر كوري للتفتيح

Degrees of chloroquine resistance in Plasmodium – Is the redox system involved? - ScienceDirect

10 It occurs when an imbalance exists between excessive production of free radicals and insufficient biological ability to remove them

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Consistent with multi-omics findings, KEGG pathway analysis identified glutathione metabolism as the most significantly perturbed shared pathway (Figure 8A), exhibiting coordinated changes between upregulated antioxidant enzymes such as Gpx3 and Mgst1 alongside depleted glutathione derivatives, supporting redox imbalance as a key pathogenic feature