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Deficiency in the level of activity of G6PDH is the basis of favism, primaquine (an antimalarial drug) sensitivity, and several other drug-sensitive hemolytic anemias, anemia and jaundice in the newborn, and chronic nonspherocytic hemolytic anemia
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Patients who titrate slowly (4-week intervals between dose increases) generate less acute oxidative stress than those who escalate every 2 weeks
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