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Although AMPK can prolong lifespan, the biosynthetic pathways required for hormones, cholesterol and other important molecules are impaired when AMPK is chronically activated

uneven skin texture

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Fsp1 knockout enhanced CaOX-induced ferroptosis in MTECs To further investigate the role of Fsp1 in oxalate-induced AKI, the CRISPR-Cas9 system was employed to create Fsp1 knockout MTECs and confirmed through Sanger sequencing and Western blot analysis (Fig