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Much of the modern enthusiasm for GHK-Cu traces to a body of gene-expression work suggesting the peptide can influence the activity of a very large number of human genes, with reviews describing modulation of thousands of gene sets involved in tissue remodeling, inflammation, and repair
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Pickart’s findings with a GHK-Cu complex that “caused old human liver tissue to synthesize proteins like younger tissue.”12 In addition to (or because of) its regenerative properties, research has found that GHK-Cu may also be able to:12 14 Reduce the appearance of fine lines and wrinkles Tighten loose skin, improve skin firmness, and reverse age-related skin thinning Promote faster wound healing Lighten the appearance of hyperpigmentation and sun damage Protect skin cells from UV damage Repair the skin barrier Smooth rough skin patches Stimulate collagen production Restore the vitality of fibroblasts (a type of cell that plays an important role in the formation of connective tissue)46 So it becomes clear why copper peptides have grown in popularity as a milder-yet-still-effective alternative to harsh actives such as retinoids, which can often cause side effects like redness, itching, burning, and peeling.47 To learn more about GHK-Cu, check out our comprehensive guide to the peptide
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