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Conclusion Addition of pioglitazone 30 mg/day to T2DM patients who did not reach the target HbA1c (≤7%) with treatment of dapagliflozin 10 mg/day and metformin over 1,000 mg/day showed effective glucose lowering efficacy without significant hypoglycemia and good tolerability with low prevalence of edema in spite of modest weight gain

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LQA_78, at doses of 20 mg/kg and 40 mg/kg, combined or not with AMB (5 mg/kg), was able to reduce the fungal infection increasing the larval lifespan when compared to untreated larvae