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Distinct systemic and gut IgA responses to bacteria of the human upper gastrointestinal tract: Cell Reports
In accordance with the role of the fumarate accumulation with cytotoxicity and oncogenic capacity, it was demonstrated that cells exposed to high levels of fumarate and succinate lead to extensive DNA fragmentation and altering the global DNA methylation patterns via DNA hypermethylation in human hepatocellular carcinoma (195)
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