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The pH changes also impede lysosomal enzyme function, which impairs endolysosome cargo degradation in autophagy, endocytosis, and phagocytosis pathways, essential in antigen processing for presentation [6] (See Figure 1)
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Artemisinin originates from isopentenyl diphosphate (IPP) or dimethylallyl diphosphate (DMAPP) via the methylerythritol phosphate (MEP) pathway in the plastid or via the mevalonate (MVA) pathway in the cytosol 70
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