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Alternatively it can be associated with inflammatory conditions such as Rheumatoid arthritis due to the overproduction of the B12 binding proteins transcobalamin and haptocorin (Christensen et al 1983: Grindulis et al, 1984), Cystic fibrosis (Lindemans etal, 1984), and patients treated with nitrous oxide (Parry etal, 1985)

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coli (Escherichia coli) , and Listeria monocytogenes