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have found that during MMP, p62 may induce autophagy by binding to the ubiquitinated VDAC1 protein localized on the OMM [278]
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In rats, curcumin replicates effects observed in mice, including reductions in serum glucose, lipid, creatinine and urea levels, and reverses proteinuria, while protecting and improving renal function [46,47,48,49,50,51,52,53,54,55,56,57]
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