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17,18 Elevated serum LDH levels are frequently associated with malignancy and are widely used as biomarkers in oncology
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For example, methylation of ACSL4 at R339 by CARM1 (also known as PRMT4) has been reported to promote RNF25-dependent ubiquitination, 70 but we did not observe ACSL4 degradation when global methylation was inhibited by the AHCY inhibitor ADOX (Figure S11J)
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