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The samples were incubated on ice for another 10 min and then centrifuged at 14,000 rpm for 25 min at 4 °C

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half-maximal effective concentration (EC 50 ) values (mean ± s.d.) of iFSP1 ( 1 ) and its derivatives ( 2 – 14 ) calculated from experiments performed at least twice in triplicate are shown in the table with the corresponding chemical structures depicted below