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(Dişel U, Kato S, Shreenivas A, Danyeli AE, Ahluwalia MS, Kurzrock R) J Immunother Precis Oncol 2026 Feb;9(1):25-31 1 FREEDOMM: Fifth-Line or Later Real-World Evaluation of Efficacy and Disease Outcomes in Multiple Myeloma with Ciltacabtagene Autoleucel: Treatment-Free Interval and Overall Survival in the USA

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Histopathological studies have demonstrated microglia exhibiting morphological features of activation—including enlarged cell bodies and retracted processes—not only in numerous animal models [457–459], but also in post-mortem human tissue samples [460, 461]