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Nutritional deficiencies after bariatric surgery | Nature Reviews Endocrinology

The published cosmetic-chemistry and wound-healing literature uses microgram amounts - roughly 1–10 μg topical per application and 50–200 μg subcutaneous, about 2–3 times weekly

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In mild cases, low levels of vitamin B12 can cause fatigue and anemia, while more serious deficiencies can lead to serious neurological and heart impairments