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This method is based on the ability of biological antioxidants in reducing Fe 3+ to Fe 2+ in the presence of 2,4,6 tripyridyl-s-triazine (TPTZ)

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In contrast, patients with progressive multiple sclerosis displayed a positive correlation between age and levels of multiple ceramides, including C14 Cer, C16 Cer, C24:1 Cer, C16 Glc Cer, and C16 Gal Cer