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Melatonin counteracts oxidative damage by neutralizing reactive oxygen species, stabilizing mitochondrial membrane potential, and preventing mPTP opening, thereby reducing activation of cell death pathways

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Importantly, Aspergillus biofilms are more resistant to antifungal drugs than are planktonic cells (415, 529, 535–538), but again, the reasons for a reduced permeability to drugs has not been explored in detail